Large study provides new insights in autism’s genetic code

Thursday, February 22, 2007

In the largest study of its kind, a genetic analysis of 1,168 families with multiple cases of autism has identified genetic links to autism. A previously overlooked stretch of DNA on chromosome 11 implicates a gene called neurexin 1 and increases the evidence for the involvement of neurexins and genes related to glutamate transmission in the brain.

Genetic studies of autism have previously been undertaken; however the new study involves the collaboration of more than 120 scientists from more than 50 institutions representing 19 countries who pooled their data as part of the Autism Genome Project. The findings were published in the Feb. 18 issue of Nature Genetics.

Bob Wright, co-founder of Autism Speaks, a non-profit organization dedicated to increasing awareness of autism, said: “The identification of susceptibility genes will provide profound new insight into the basis of autism offering a route to breakthroughs in new treatments in support of families.” Autism Speaks funded this project in conjunction with the U.S. National Institutes of Health.

Joachim Hallmayer, MD, associate professor of psychiatry at Stanford and chair of the collaboration’s executive committee, explains what is next: “While promising, these results need to be followed up with more refined genetic maps to home in on other specific candidate genes. We also need to look more closely at chromosomal anomalies in large samples of children with autism.” In the paper, researchers caution that the genetic foundation of autism probably involves multiple genes and chromosomal abnormalities.

Autism affects about one in every 150 children, and the CDC has called it an “urgent health concern”. Autism is a developmental disorder which impairs social interaction, communication and features restricted and repetitive interests and activities. Twin studies and other research clearly suggest a genetic basis for the condition. Currently there is no cure for autism, but both behavioral or sensory interventions and drugs can influence the symptoms.

Saturday, February 19, 2005

Feel free to use the Wikimedia sites to solve our Wikinews crossword. Please do not fill it out online as it would spoil it for other people; print it out and fill it in at your own leisure!

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Saturday, April 17, 2010

In a new setback to the Thai government’s efforts to ease mounting political tensions, protest leaders escaped from their hotel Friday after security forces arrived to arrest them.

One, Arisman Pongruangrong, climbed down three floors using a rope, and was rushed away by supporters thronging the building. The police say Arisman led recent rallies at the national parliament, the election commission, and satellite transmission bases.

Officials earlier Friday said the government is preparing to arrest people linked to violent clashes with security forces last Saturday.

Deputy Prime Minister Suthep Thaugsuban, Thai security chief, announced the raid on the hotel as it was unfolding, saying that a Special Forces unit had closed in around a downtown Bangkok hotel.

“As I am speaking, the government’s special team is surrounding the SC Park Hotel, where we have learned that there are terrorists and some of their leaders hiding,” Suthep said.

A spokesman for the governing Democrat Party, Baranuj Smuthararaks, says arrest warrants have been issued for those suspected of being involved in the violence. Some of the suspects have been identified from photos taken during the clashes.

“Right now the government’s focusing on issuing warrants for acts of terrorism by the people who fortunately have been captured in action [in photos] by both the local and international media,” he said.

According to the New York Times, as many as five protest leaders had been staying at the same hotel as Pongruangrong. Those leaders later appeared together at a protest rally in Bangkok.

“I would like to thank all of the people who saved me,” Arisman said. “You have saved democracy.”The government says armed men infiltrated protester ranks Saturday and fired on troops trying to disperse a rally. Five soldiers and 19 protesters died during the clashes.

Thailand is facing its most severe political crisis in almost 20 years. The anti-government movement, led by the United Democratic Front against Dictatorship or UDD, demands that the government step down and call fresh elections.

UDD supporters, known as red shirts, have held protests in Bangkok for more than a month.

The UDD largely supports former Prime Minister Thaksin Shinawatra, who was ousted in a coup in 2006 and remains overseas to avoid a jail sentence for corruption. Mr. Thaksin has strong support among the rural and urban poor, as well among some sections of the army and police.

Some parties in the governing coalition want to set a clear time frame for elections to ease tensions. But the government says it will only call elections once the political situation has cooled.

Tuesday, May 31, 2016

Today, Joachim Löw, manager of the German national football team, dropped Borussia Dortmund midfielder Marco Reus from the UEFA Euro 2016 squad. Marco Reus, who turned 27 years old today, is suffering from a groin injury. He also missed the 2014 FIFA World Cup with an ankle injury.

Löw said their medical staff wasn’t sure Reus could meet the demands of the forthcoming games. He added, “Marco has serious fitness problems; he can only run in a straight line at the moment.” ^{((de))German language: ?Marco hat massive gesundheitliche Probleme, im Moment kann er nur geradeaus laufen.}

Löw also did not include other Bundesliga players Karim Bellarabi, Julian Brandt, and Sebastian Rudy from the provisional squad in the final selection. Thanking the four German internationals for their performance in training, he said, “It’s not a decision against those four players, but rather one in favour of the other 23.” ^{((de))German language: ?Es ist keine Entscheidung gegen vier Spieler, sondern eine Entscheidung für 23 Spieler.}

Germany are due to play their final friendly match before the start of Euro 2016 on June 4 against Hungary. On June 12, Germany will open their account in Euro 2016 when they face Ukraine in Lille, France.

Tuesday, August 14, 2012

San Fernando, Chile — Ten students from the Liceo María Luisa Bombal of Rancagua, O’Higgins Region were detained by the local police yesterday. Following their release, the students told the media they were required to remove their clothes at the police station.

The students, seven men and three women, took control of the building of the school early yesterday morning in response to the long delay in re-construction of the liceo, following the earthquake of 2010. At around 08:00 local time (1200 UTC), Leonardo Fuentes, general secretary of the Municipal Educational Corporation of Rancagua, authorized the police to clear out the students.

Student leader Jennifer Olivares told Diario VI Región the police “stripped off [their] clothes” ^{((es))Spanish language: ?Al llegar a la comisaría nos desnudaron.} upon their arrival at the police station, Comisaría de Rancagua, something which Lieutenant Colonel of Carabineros Iván Guajardo did not deny. However, police stated the students will be charged by the public prosecutor with robbing food from the school. “It’s a bit illogical that they stripped off our clothes, with the knowledge that there were minors and without [us] being delinquents, but students who took the school peacefully” ^{((es))Spanish language: ?Es un poco ilógico que nos desnuden habiendo menores de edad y no siendo delincuentes, sino estudiantes que estábamos en una toma que había sido pacífica}, said Olivares. Ignacio Muñoz, former leader of the occupation of the Liceo María Luisa Bombal, told El Rancahuaso “the Mayor [Eduardo Soto] promised to begin the reconstruction works last summer, and it’s August already and they don’t even begin to take the debris outside” ^{((es))Spanish language: ?El alcalde se comprometió a comenzar los trabajos de reconstrucción durante el verano de este año, y ya estamos en agosto y aún no comienzan ni moviendo los escombros del interior}. Education Regional Secretary (Seremi de Educación) Pedro Larraín said the government “does not share” ^{((es))Spanish language: ?No compartimos las tomas} such actions, “because they harm education” ^{((es))Spanish language: ?porque perjudican a la educación}.

The Region of Libertador General Bernardo O’Higgins was one of the first in 2012 to resuscitate the previous year’s student protests, more specifically at the Liceo Industrial de San Fernando, which was taken control by the students in late July, and which as of yesterday was still taken. The students of the Liceo Industrial were particularly affected, after the president of the school’s centro de alumnos Guillermo Horta Farías was stabbed outside the educational establishment on July 31; his fellow schoolmates subsequently organized a march in his honour in Rancagua, on August 8. As of August 11, eight high schools have been taken control of by students, in response to the government’s failure to satisfy the secondary and university students’ requests.

Friday, October 21, 2016

The following is the fifth edition of a monthly series chronicling the U.S. 2016 presidential election. It features original material compiled throughout the previous month after an overview of the month’s biggest stories.

In this month’s edition on the campaign trail: an arrest warrant is issued for the Green Party presidential and vice presidential nominees; the “Birther King” opens up about Donald Trump’s changing view on President Obama’s place of birth; and Wikinews interviews a write-in presidential candidate hoping to run the “most libertarian” campaign in history.